AEGIS VES 240® Disinfectant: How It Works

AEGIS VES 240® helps remove unwanted germs from surfaces, and the active ingredient is free from bleach, dyes, and phosphates. It has a long and safe history of use against a broad spectrum of viruses, bacteria, and fungi. The chart below provides a few select organisms; please contact your account manager or view the label for a complete listing:

AEGIS® VES 240 IS EFFECTIVE AGAINST:

Bacteria:

Viruses:

Pseudomonas aeruginosa

*Hepatitis B Virus

Salmonella enterica

*Hepatitis C Virus

Staphylococcus aureus

*Herpes Simplex Virus Type 1

Acinetobacter baumannii

*Herpes Simplex Virus Type 2

Bordetella bronchiseptica

*Human Coronavirus

Bordetella pertussis

*Respiratory Syncytial Virus

Campylobacter jejuni

*Rotavirus

Enterobacter aerogenes at 1:64 dilution

*SARS-Related Coronavirus 2

Enterococcus faecalis

*Vaccinia

Enterococcus faecalis - Vancomycin resistant

*HIV-1

ESBL Escherichia coli

*Influenza Type A / Hong Kong

Escherichia coli

*Enterovirus D68 at 1:64 dilution

Escherichia coli O157:H7

*Norovirus

Klebsiella pneumoniae

*Feline Calicivirus at 1:64 dilution

Carbapenem-resistant

Fungi:

Listeria monocytogenes

Candida albicans

Proteus vulgaris

Trichophyton mentagrophytes

Serratia marcescens at 1:64 dilution

AEGIS® VES 240 IS EFFECTIVE AGAINST:

BACTERIA:
Pseudomonas aeruginosa
Salmonella enterica
Staphylococcus aureus
Acinetobacter baumannii
Bordetella bronchiseptica
Bordetella pertussis
Campylobacter jejuni
Enterobacter aerogenes at 1:64 dilution
Enterococcus faecalis
Enterococcus faecalis - Vancomycin resistant
ESBL Escherichia coli
Escherichia coli
Escherichia coli O157:H7
Klebsiella pneumoniae
Carbapenem-resistant

VIRUSES:
*Hepatitis B Virus
*Hepatitis C Virus
*Herpes Simplex Virus Type 1
*Herpes Simplex Virus Type 2
*Human Coronavirus
*Respiratory Syncytial Virus
*Rotavirus
*SARS-Related Coronavirus 2
*Vaccinia
*HIV-1
*Influenza Type A / Hong Kong
*Enterovirus D68 at 1:64 dilution
*Norovirus
*Feline Calicivirus at 1:64 dilution

FUNGI:
Candida albicans
Trichophyton mentagrophytes

AEGIS® Disinfectant: How It Works

Microbes are naturally occurring microorganisms that multiply when they attach to surfaces and absorb its available nutrients. While they can survive under a variety of conditions, they thrive in warm, humid, moisture-rich environments. Soils and other organic matter present on or within building materials, furnishings, and other objects provide these microorganisms a rich source of nutrients.

Cleaning is the removal of germs, soil, dirt, debris, salts, oils, blood from objects or surfaces. While regular cleaning practices are important, germs are not killed. AEGIS VES 240 disinfection protection is applied to inanimate surfaces or objects to kill and inactivate contaminating microbes. This disinfectant use is a critical step in destroying viruses, bacteria, and fungi, contributing to a systems approach to clean.

The mechanisms of the disinfecting action of AEGIS VES 240®

Quaternary ammonium salts (QAS) are also commonly called “Quats.” Multi-Quat Disinfectant, like AEGIS VES 240, contains a combination of different QAS as the active component. QAS are cationic molecules that possess antimicrobial activity against a wide range of microbes, including Gram-Positive and Gram-Negative bacteria, fungi, and some viruses.

In its most basic form, quaternary ammonium is a permanently charged cation with a central nitrogen atom surrounded by four R-groups, most commonly alkyl or aryl groups. Chemically, QAS are organically substituted ammonium compounds in which the nitrogen atom has a valence of 5. Four of the substituent radicals (R1-R4) are alkyl or heterocyclic radicals of a given size or chain length, and the fifth (X-) is a halide, sulfate, or similar radical. Each compound exhibits its own antimicrobial characteristics. Some quaternary ammonium compounds remain active in hard water and are tolerant of anionic residues. The activity and efficacy of a QAS is dependent on the length of the alkyl chain, the presence of a perfluorinated group, and the number of cationic ammonium groups.

The antimicrobial activity of QAS is primarily attributed to the disruption of the microbial cell membrane. Specifically, the positively charged QAS interact with the negatively charged cell membrane and membrane-bound proteins of the microbial cell. This interaction disrupts the membrane function, causing eventual lysing of the cell membrane and subsequent leakage of cytoplasmic materials. Additional modes of action by QAS include the inactivation of energy-producing enzymes and denaturation of essential cell proteins. In some instances, QAS may interact with bacterial DNA, thus inhibiting cellular replication.

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